Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | THRA | P10827 | 9/20 | 0.62 |
| ▸ | THRB | P10828 | 9/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135443 | 0.95 | L3MBTL1 (0.78) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL3145220 | 0.93 | L3MBTL1 (0.76) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL9356282 | 0.93 | L3MBTL1 (0.76) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL3130654 | 0.93 | L3MBTL1 (0.76) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL9815969 | 0.93 | L3MBTL1 (0.76) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL3145641 | 0.93 | L3MBTL1 (0.76) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL10523939 | 0.93 | L3MBTL1 (0.76) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL30089476 | 0.93 | THRA (0.70) | L3MBTL1THRATHRBHSD17B10ALDH1A1 | |
| Butylbenzyl SCHEMBL8119801 | 0.92 | L3MBTL1 (0.69) | L3MBTL1THRATHRBALDH1A1RARB | |
| SCHEMBL8754744 | 0.91 | L3MBTL1 (0.71) | L3MBTL1THRATHRBALDH1A1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4871771-A | PHENYL SUBSTITUTED-DITHIA-ALKANEDIOIC ACIDS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0327306-A2 | Leukotriene B4 antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4730005-A | DITHIA-ALKANEDIOIC ACIDS | SMITHKLINE BECKMAN CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0253501-A2 | N-disubstituted cycloalkylmethyl amines useful as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |
| EP-0251466-A2 | Chemical process for the preparation of esters of substituted cyclopropyl caboxylic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-07 | — | — | EP | disclosed |
| EP-0168902-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0168902-A1 | Leukotriene antagonists | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |