Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834035 | 0.93 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9563431 | 0.92 | SMN1; SMN2 (0.46) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7812297 | 0.90 | KMT2A (0.42) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7835953 | 0.90 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7830610 | 0.90 | SLC10A2 (0.47) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7809634 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7830548 | 0.88 | SLC10A2 (0.46) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL9563414 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL8138537 | 0.88 | SLC10A2 (0.46) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL7801628 | 0.88 | KMT2A (0.41) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686630-B1 | Quinoline derivatives and pharmaceutical composition containing them | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5641788-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0686630-A1 | Quinoline derivatives and pharmaceutical composition containing them | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-13 | — | — | EP | disclosed |