Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190382 | 0.80 | ALDH1A1 (0.51) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL31664216 | 0.80 | ALDH1A1 (0.51) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL30689781 | 0.79 | HTT (0.46) | HTTALDH1A1MAPTKMT2AKAT6A | |
| SCHEMBL3252726 | 0.79 | HTT (0.46) | HTTALDH1A1MAPTKMT2AKAT6A | |
| SCHEMBL1665951 | 0.79 | MAPT (0.69) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL29603325 | 0.79 | MAPT (0.59) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL152563 | 0.79 | MAPT (0.59) | LMNAHTTALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL4229730 | 0.77 | MAPT (0.58) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL9191986 | 0.77 | MAPT (0.58) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL27617245 | 0.77 | MAPT (0.58) | LMNAHTTALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |