Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817509 | 0.90 | S1PR1 (0.56) | S1PR1S1PR3MEN1KMT2ANAMPT | |
| SCHEMBL7813474 | 0.84 | S1PR1 (0.51) | S1PR1S1PR3MEN1KMT2ANAMPT | |
| SCHEMBL7813924 | 0.78 | PPARA (0.51) | MEN1KMT2ANAMPTSIGMAR1HPGD | |
| SCHEMBL7817803 | 0.77 | MAPT (0.55) | MEN1KMT2ADRD1PTGER2HRH4 | |
| SCHEMBL7813977 | 0.77 | S1PR1 (0.52) | S1PR1S1PR3MEN1KMT2APTGER2 | |
| SCHEMBL7809992 | 0.76 | ALDH1A1 (0.52) | S1PR1MEN1KMT2ADRD1PTGER2 | |
| SCHEMBL4670397 | 0.75 | HRH3 (0.75) | MEN1KMT2AHRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7804410 | 0.75 | CA12 (0.57) | MEN1KMT2ADRD1PTGER2HRH4 | |
| SCHEMBL1822418 | 0.74 | L3MBTL1 (0.67) | MEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL24303917 | 0.73 | NAMPT (0.56) | NAMPTSIGMAR1NPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |