Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813846 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KDM4EPKMMAPTHTT | |
| SCHEMBL5046634 | 0.84 | NPC1 (0.74) | ALDH1A1KDM4EPKMSMN1; SMN2NPC1 | |
| SCHEMBL5046637 | 0.84 | NPC1 (0.74) | ALDH1A1KDM4EPKMSMN1; SMN2NPC1 | |
| SCHEMBL11140030 | 0.82 | KDM4E (0.81) | ALDH1A1KDM4EPKMMAPTHTT | |
| SCHEMBL11140025 | 0.82 | KDM4E (0.81) | ALDH1A1KDM4EPKMMAPTHTT | |
| SCHEMBL11873425 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EPKMMEN1KMT2A | |
| SCHEMBL29505834 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EPKMMEN1KMT2A | |
| SCHEMBL1008398 | 0.79 | POLB (0.63) | ALDH1A1KDM4EMAPTHTTMEN1 | |
| SCHEMBL3224674 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EPKMMAPTHTT | |
| SCHEMBL3224656 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EPKMMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |