Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144647 | 0.89 | CTRC (0.63) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL28349098 | 0.87 | TP53 (0.59) | CTRCPPARAPPARGTP53TSHR | |
| SCHEMBL2255421 | 0.87 | TP53 (0.59) | CTRCPPARAPPARGTP53TSHR | |
| SCHEMBL8133487 | 0.87 | TP53 (0.59) | CTRCPPARAPPARGTP53TSHR | |
| SCHEMBL15218606 | 0.87 | CTRC (0.52) | CTRCPPARAPPARGRAB9ANPC1 | |
| SCHEMBL15218608 | 0.87 | MAPT (0.57) | CTRCRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL15218607 | 0.87 | MAPT (0.57) | CTRCRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL11589038 | 0.86 | TP53 (0.56) | CTRCPPARAPPARGPTGESALOX5 | |
| SCHEMBL11854295 | 0.86 | CTRC (0.58) | CTRCPPARAPPARGALDH2PTGES | |
| SCHEMBL2720955 | 0.84 | CTRC (0.54) | CTRCPPARAPPARGALDH2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |