Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15218607 | 1.00 | MAPT (0.57) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL15218606 | 0.95 | CTRC (0.52) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL7814101 | 0.87 | CTRC (0.54) | MAPTNPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL31144647 | 0.86 | CTRC (0.63) | TSHRSMN1; SMN2CTRCTP53 | |
| SCHEMBL28349098 | 0.85 | TP53 (0.59) | TSHRCTRCKMT2ATP53 | |
| SCHEMBL8133487 | 0.85 | TP53 (0.59) | TSHRCTRCKMT2ATP53 | |
| SCHEMBL15199291 | 0.85 | CTRC (0.63) | TSHRLMNACTRCTP53 | |
| SCHEMBL2255421 | 0.85 | TP53 (0.59) | TSHRCTRCKMT2ATP53 | |
| SCHEMBL11589038 | 0.84 | TP53 (0.56) | TSHRCTRCKMT2ATP53 | |
| SCHEMBL13152977 | 0.83 | ESR1 (0.57) | MAPTALDH1A1NPC1RAB9ASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475750-B2 | Phenylketone carboxylate compounds and pharmaceutical uses thereof | PROMETIC BIOSCIENCES INC. (CA) | 2016-10-25 | — | — | US | disclosed |
| US-20130225681-A1 | Phenylketone Carboxylate Compounds and Pharmaceutical Uses Thereof | PROMETIC BIOSCIENCES INC. (CA) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225681-A1 | Phenylketone Carboxylate Compounds and Pharmaceutical Uses Thereof | BCKDK, PDK4, FAH | MAPT 801/4885ALDH1A1 1168/4885NPC1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.