Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.77 |
| ▸ | FAAH | O00519 | 3/20 | 0.68 |
| ▸ | CCR2 | P41597 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814197 | 0.93 | CCR3 (0.77) | CCR3FAAHCCR2 | |
| SCHEMBL5353025 | 0.88 | CCR3 (0.70) | CCR3FAAHCCR2 | |
| SCHEMBL5351408 | 0.88 | CCR3 (1.00) | CCR3 | |
| SCHEMBL5358819 | 0.87 | FAAH (0.85) | CCR3FAAHKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7825001 | 0.87 | CCR3 (0.76) | CCR3FAAH | |
| SCHEMBL7826536 | 0.87 | CCR3 (0.75) | CCR3FAAH | |
| SCHEMBL7824997 | 0.85 | CCR3 (0.73) | CCR3FAAH | |
| SCHEMBL5358054 | 0.84 | CCR3 (0.66) | CCR3FAAHCCR2KCNH2 | |
| SCHEMBL7814917 | 0.83 | CCR3 (0.77) | CCR3FAAH | |
| SCHEMBL1943895 | 0.83 | CCR2 (0.76) | CCR3CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |