SCHEMBL7814526

SCHEMBL7814526

Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)N4CCC[C@H]4C(=O)N4CCN(C(=N)N)CC4)c3Cl)c2n1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 8/20 0.68
RORC P51449 12/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814521 1.00 BDKRB2 (0.68) BDKRB2RORC
Hydrochloric Acid SCHEMBL7959552 0.99 BDKRB2 (0.67) BDKRB2RORC
Hydrochloric Acid SCHEMBL7959551 0.99 BDKRB2 (0.67) BDKRB2RORC
SCHEMBL7811001 0.92 RORC (0.60) BDKRB2RORC
SCHEMBL7810997 0.92 RORC (0.60) BDKRB2RORC
SCHEMBL7812543 0.92 BDKRB2 (0.61) BDKRB2RORC
SCHEMBL7812545 0.92 BDKRB2 (0.61) BDKRB2RORC
SCHEMBL7805385 0.92 RORC (0.60) BDKRB2RORC
SCHEMBL7805388 0.92 RORC (0.60) BDKRB2RORC
Hydrochloric Acid SCHEMBL8186235 0.91 BDKRB2 (0.61) BDKRB2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874841-B1 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS FOURNIER IND & SANTE (FR) 2001-10-04 EP disclosed