SCHEMBL7814570

SCHEMBL7814570

CCCCOC1(O)C([N+](=O)[O-])=CC=CC1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
PLA2G4B P0C869 1/20 0.32
MGLL Q99685 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
CACNA1F O60840 1/20 0.30
CACNA1D Q01668 1/20 0.30
CACNA1S Q13698 1/20 0.30
CACNA1C Q13936 1/20 0.30
HCAR3 P49019 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2293122 0.70
SCHEMBL8948679 0.70 LMNA (0.34) ALDH1A1TSHR
SCHEMBL10964461 0.69
SCHEMBL4101948 0.65 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9687455 0.64
SCHEMBL20503228 0.63 PPARG (0.34) PLA2G4BTP53TSHR
SCHEMBL15623074 0.62
SCHEMBL28026706 0.62
SCHEMBL4119758 0.62
SCHEMBL6019196 0.62 S1PR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1314906-A Salts of paroxetine SMITHKLINE BEECHAM PLC (GB) 2001-09-26 CN disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed