SCHEMBL7814573

SCHEMBL7814573

Cc1n[nH]c(O)c1C(=O)c1ccc(S(C)(=O)=O)c(OCC2CCO2)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.32
GRM5 P41594 2/20 0.31
PRKAB2 O43741 1/20 0.31
PRKAG1 P54619 1/20 0.31
PRKAA2 P54646 1/20 0.31
PRKAA1 Q13131 1/20 0.31
PRKAG3 Q9UGI9 1/20 0.31
PRKAG2 Q9UGJ0 1/20 0.31
PRKAB1 Q9Y478 1/20 0.31
SCN9A Q15858 1/20 0.31
MAPK1 P28482 1/20 0.31
P2RX4 Q99571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808943 0.91 CNR2 (0.32) GRM5SCN9AMAPK1
SCHEMBL8175813 0.83 RORC (0.34) RORCGRM5SCN9AP2RX4
SCHEMBL7810791 0.82 RORC (0.33) RORCMAPK1
SCHEMBL7809075 0.81 GNRHR (0.34)
SCHEMBL7811746 0.80 FPR2 (0.30)
SCHEMBL8183401 0.78 RORC (0.34) RORCGRM5PRKAB2PRKAG1PRKAA2
SCHEMBL7814563 0.77 CYP1A2 (0.32)
SCHEMBL8168638 0.77 RORC (0.33) RORCGRM5SCN9AMAPK1P2RX4
SCHEMBL15649864 0.73
SCHEMBL15649177 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1077972-A1 1-ALKYL-4-[(3-OXETANYL-)BENZOYL]-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 2001-02-28 EP disclosed
WO-2000017194-A1 1-ALKYL-4-[(3-OXETANYL-)BENZOYL]-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2000-03-30 WO disclosed