Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 3/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586774 | 0.91 | POLB (0.62) | POLBMAPTALDH1A1HSP90AA1LMNA | |
| SCHEMBL503711 | 0.80 | HSP90AA1 (0.55) | POLBMAPTALDH1A1HSP90AA1LMNA | |
| SCHEMBL4585368 | 0.79 | PTPRC (0.57) | POLBMAPTALDH1A1HSP90AA1LMNA | |
| SCHEMBL4586700 | 0.76 | PTPRC (0.54) | POLBMAPTALDH1A1HSP90AA1LMNA | |
| Valeric Acid SCHEMBL27533209 | 0.75 | PTPRC (0.57) | MAPTALDH1A1PTPRCS100A4BCHE | |
| SCHEMBL27533208 | 0.72 | PTPRC (0.46) | MAPTALDH1A1PTPRCS100A4BCHE | |
| SCHEMBL4586255 | 0.72 | PTPRC (0.51) | MAPTALDH1A1HSP90AA1PTPRCS100A4 | |
| SCHEMBL28315490 | 0.71 | PTPRC (0.64) | MAPTALDH1A1HSP90AA1LMNAPTPRC | |
| SCHEMBL28264261 | 0.71 | PTPRC (0.64) | MAPTALDH1A1HSP90AA1LMNAPTPRC | |
| SCHEMBL10492712 | 0.70 | POLB (0.70) | POLBMAPTALDH1A1LMNAPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |