SCHEMBL503711

SCHEMBL503711

O=C(O)c1cccc2c1-c1ccc([N+](=O)[O-])cc1C2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.55
PTPRC P08575 3/20 0.55
S100A4 P26447 2/20 0.55
BCHE P06276 1/20 0.55
ACHE P22303 1/20 0.55
CES1 P23141 1/20 0.55
ALDH1A1 P00352 4/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 2/20 0.50
ERO1A Q96HE7 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
CYP1A2 P05177 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586774 0.89 POLB (0.62) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL5707981 0.86 PTPRC (0.56) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL9182723 0.84 PTPRC (0.50) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL11201112 0.84 ERO1A (0.54) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL7814726 0.80 POLB (0.52) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL10526604 0.80 PTPRC (0.51) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL8100705 0.80 S100A4 (0.66) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL4586255 0.80 PTPRC (0.51) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL6647847 0.78 PTPRC (0.59) HSP90AA1PTPRCS100A4BCHEACHE
SCHEMBL10526597 0.78 TTR (0.67) HSP90AA1PTPRCBCHEALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11591294-B2 Fluorenone/fluorenol derivatives for aqueous redox flow batteries BATTELLE MEMORIAL INSTITUTE (US) 2023-02-28 US claimed
US-20210147347-A1 FLUORENONE/FLUORENOL DERIVATIVES FOR AQUEOUS REDOX FLOW BATTERIES BATTELLE MEMORIAL INSTITUTE (US) 2021-05-20 US claimed
EP-0147226-B1 VISIBLE LIGHT ABSORBING PEROXY ESTERS LOCTITE CORPORATION (US) 1989-11-23 EP claimed
US-4604295-A VISIBLE AND UV PHOTOINITIATORS FOR CURING ACRYLIC MONOMERS AND PREPOLYMERS LOCTITE CORPORATION (US) 1986-08-05 US claimed
EP-0147226-A2 Visible light absorbing peroxy esters LOCTITE CORPORATION (US) 1985-07-03 EP claimed
US-11591294-B2 Fluorenone/fluorenol derivatives for aqueous redox flow batteries BATTELLE MEMORIAL INSTITUTE (US) 2023-02-28 US disclosed
US-20210147347-A1 FLUORENONE/FLUORENOL DERIVATIVES FOR AQUEOUS REDOX FLOW BATTERIES BATTELLE MEMORIAL INSTITUTE (US) 2021-05-20 US disclosed
EP-2151846-B1 High temperature thermal cutoff device THERM O DISC INC (US) 2013-10-09 EP disclosed
CN-101203518-B Fluorene derivative, composition containing the same and use thereof AVENTIS PHARMA SA 2013-07-24 CN disclosed
US-8435718-B2 Upper layer-forming composition and photoresist patterning method JSR CORPORATION (JP) 2013-05-07 US disclosed
EP-1950610-B1 IMMERSION LITHOGRAPHIC COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN JSR CORP (JP) 2012-05-02 EP disclosed
US-20120028198-A1 UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD JSR CORPORATION (JP) 2012-02-02 US disclosed
EP-1950610-A1 COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN JSR Corporation (JP) 2008-07-30 EP disclosed
US-20080153837-A1 Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof AVENTIS PHARMA S.A. (FR) 2008-06-26 US disclosed
CN-101203518-A Novel fluorene derivatives, compositions containing same and uses thereof AVENTIS PHARMA SA (FR) 2008-06-18 CN disclosed
US-7157452-B2 Substituted 4,9-dihydrocyclopenta{imn}phenanthridine-5-ones derivatives thereof and their uses MGI GP, INC. (US) 2007-01-02 US disclosed
US-7157452-B2 Substituted 4,9-dihydrocyclopenta{imn}phenanthridine-5-ones derivatives thereof and their uses MGI GP, INC. (US) 2007-01-02 US disclosed
EP-0147226-B1 VISIBLE LIGHT ABSORBING PEROXY ESTERS LOCTITE CORPORATION (US) 1989-11-23 EP disclosed
US-4604295-A VISIBLE AND UV PHOTOINITIATORS FOR CURING ACRYLIC MONOMERS AND PREPOLYMERS LOCTITE CORPORATION (US) 1986-08-05 US disclosed
EP-0147226-A2 Visible light absorbing peroxy esters LOCTITE CORPORATION (US) 1985-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591294-B2 Fluorenone/fluorenol derivatives for aqueous redox flow batteries NDUFV1, SCO2, NDUFS4 HSP90AA1 4434/4885PTPRC 3168/4885S100A4 390/4885
US-20210147347-A1 FLUORENONE/FLUORENOL DERIVATIVES FOR AQUEOUS REDOX FLOW BATTERIES NDUFV1, SCO2, NDUFS4 HSP90AA1 4434/4885PTPRC 3168/4885S100A4 390/4885
US-20080153837-A1 Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof HSP90B1, HSP90AB1, HSP90AA1 HSP90AA1 3/4885PTPRC 1389/4885S100A4 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.