Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827684 | 0.95 | CCR3 (0.64) | CCR3ALDH1A1 | |
| SCHEMBL7821497 | 0.90 | CCR3 (0.57) | CCR3ALDH1A1CCR2KMT2A | |
| SCHEMBL7824203 | 0.90 | CCR3 (0.75) | CCR3ALDH1A1THRBALOX12KMT2A | |
| SCHEMBL7815115 | 0.87 | CCR3 (0.84) | CCR3 | |
| SCHEMBL7821639 | 0.86 | CCR3 (0.65) | CCR3 | |
| SCHEMBL7829373 | 0.85 | CCR3 (0.77) | CCR3ALDH1A1 | |
| SCHEMBL7813828 | 0.83 | CCR3 (0.64) | CCR3ALDH1A1 | |
| SCHEMBL7825484 | 0.81 | CCR3 (0.50) | CCR3 | |
| SCHEMBL7829620 | 0.80 | CCR3 (0.75) | CCR3 | |
| SCHEMBL7813749 | 0.80 | CCR3 (0.67) | CCR3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |