SCHEMBL7825484

SCHEMBL7825484

O=C(Nc1ccccc1C12CC3CC(CC(C3)C1)C2)N1CCCCC1CCN1CCC(Cc2ccc(F)cc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 16/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7825777 0.92 CCR3 (0.59) CCR3
SCHEMBL7829266 0.84 CCR3 (0.60) CCR3
SCHEMBL7827684 0.82 CCR3 (0.64) CCR3
SCHEMBL7814938 0.81 CCR3 (0.62) CCR3
SCHEMBL7823461 0.79 CCR3 (0.59) CCR3
SCHEMBL7828570 0.76 CCR3 (0.60) CCR3
SCHEMBL7815115 0.75 CCR3 (0.84) CCR3
SCHEMBL7821639 0.74 CCR3 (0.65) CCR3
SCHEMBL7829373 0.73 CCR3 (0.77) CCR3
SCHEMBL7821497 0.73 CCR3 (0.57) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140834-A1 HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-10-10 EP disclosed
WO-2000035877-A1 HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 WO disclosed