Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814938 | 0.95 | CCR3 (0.62) | CCR3ALDH1A1 | |
| SCHEMBL7829373 | 0.90 | CCR3 (0.77) | CCR3ALDH1A1FAAH | |
| SCHEMBL7815115 | 0.88 | CCR3 (0.84) | CCR3 | |
| SCHEMBL7821639 | 0.87 | CCR3 (0.65) | CCR3 | |
| SCHEMBL7821497 | 0.85 | CCR3 (0.57) | CCR3ALDH1A1 | |
| SCHEMBL7824203 | 0.85 | CCR3 (0.75) | CCR3ALDH1A1 | |
| SCHEMBL7813828 | 0.84 | CCR3 (0.64) | CCR3ALDH1A1 | |
| SCHEMBL7825484 | 0.82 | CCR3 (0.50) | CCR3 | |
| SCHEMBL7820927 | 0.82 | CCR3 (0.70) | CCR3FAAH | |
| SCHEMBL7814917 | 0.82 | CCR3 (0.77) | CCR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |