Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997939 | 1.00 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL389036 | 0.92 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL389037 | 0.92 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL30475600 | 0.92 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL8007402 | 0.91 | PPARG (0.86) | PPARGPPARA | |
| SCHEMBL7824139 | 0.90 | PPARG (0.83) | PPARGPPARA | |
| SCHEMBL7825955 | 0.89 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9270271 | 0.89 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL7825493 | 0.89 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL3106722 | 0.89 | PPARG (0.84) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648212-B1 | BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 2001-10-24 | — | — | EP | claimed |
| EP-0648212-B1 | BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES AS PHARMACEUTICAL | SMITHKLINE BEECHAM PLC (GB) | 2001-10-24 | — | — | EP | disclosed |
| US-6166049-A | Use of an antagonist of PPARα and PPARγ for the treatment of syndrome X | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-26 | — | — | US | disclosed |
| EP-1000938-A1 | Heterocyclic compounds as pharmaceuticals | SMITHKLINE BEECHAM PLC (GB) | 2000-05-17 | — | — | EP | disclosed |
| US-6048883-A | HYPOGLYCEMIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |
| EP-0879053-A1 | USE OF AN ANTAGONIST OF PPAR-ALPHA AND PPAR-GAMMA FOR THE TREATMENT OF SYNDROM X | SMITHKLINE BEECHAM PLC (GB) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997025042-A1 | USE OF AN AGONIST OF PPAR-ALPHA AND PPAR-GAMMA FOR THE TREATMENT OF SYNDROM X | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-07-17 | — | — | WO | disclosed |
| EP-0772605-A1 | BENZOXAZOLES AND PYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF THE TYPE II DIABETES | SMITHKLINE BEECHAM PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004261-A1 | BENZOXAZOLES AND PRYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF THE TYPE II DIABETES | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |
| WO-1996004260-A1 | BENZOXAZOLES AND PYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF THE TYPE II DIABETES | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |