SCHEMBL7815341

SCHEMBL7815341

CCN(CCC(=O)O)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.79
KMT2A Q03164 3/20 0.79
NPC1 O15118 1/20 0.79
POLB P06746 1/20 0.79
RAB9A P51151 1/20 0.79
SCP2 P22307 1/20 0.66
GPR84 Q9NQS5 10/20 0.47
PTPRA P18433 1/20 0.46
PTPRB P23467 1/20 0.46
ALDH1A1 P00352 3/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
BRCA1 P38398 1/20 0.42
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nile Red SCHEMBL29373685 0.89 MEN1 (1.00) MEN1KMT2ANPC1POLBRAB9A
Nile Red SCHEMBL49047 0.89 MEN1 (1.00) MEN1KMT2ANPC1POLBRAB9A
Nile Red SCHEMBL28703996 0.88 MEN1 (0.93) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL18072729 0.83 SCP2 (0.62) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL23266942 0.80 MEN1 (0.78) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL15398206 0.80 MEN1 (0.78) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL15398222 0.80 MEN1 (0.78) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL14267417 0.80 SCP2 (1.00) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL31722939 0.80 NPC1 (0.74) MEN1KMT2ANPC1POLBRAB9A
SCHEMBL14986327 0.80 NPC1 (0.74) MEN1KMT2ANPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885263-B1 BENZOPHENOXAZINE DYES AMERSHAM PHARM BIOTECH UK LTD (GB) 2001-04-25 EP claimed
US-6166202-A Benzophenoxazine dyes AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) 2000-12-26 US claimed
EP-0885263-A1 BENZOPHENOXAZINE DYES Amersham Pharmacia Biotech UK Limited (GB) 1998-12-23 EP claimed
WO-1997029154-A1 BENZOPHENOXAZINE DYES AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) 1997-08-14 WO claimed