SCHEMBL7815772

SCHEMBL7815772

Fc1cccc(F)c1C1=NC(COc2ccc(Oc3ccc(C(F)(F)F)cc3Cl)cc2)CO1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.41
MRGPRX4 Q96LA9 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808387 0.94 FFAR1 (0.42) FFAR1MRGPRX4
SCHEMBL8891146 0.92 FFAR1 (0.40) FFAR1
SCHEMBL7812063 0.87 HPGD (0.43) TAAR1
SCHEMBL7809988 0.86 RAB9A (0.47) FFAR1
SCHEMBL8893119 0.83 MRGPRX4 (0.42) MRGPRX4
SCHEMBL7803670 0.83 TAAR1 (0.37) TAAR1
SCHEMBL7808652 0.83 PTGES (0.36) MRGPRX4TAAR1
SCHEMBL7815921 0.82 MAPK1 (0.43)
SCHEMBL7808420 0.81 ACACB (0.38) MRGPRX4TAAR1
SCHEMBL7803617 0.81 TAAR1 (0.46) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP claimed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US claimed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP claimed
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed