⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508040 | 1.00 | — | — | |
| SCHEMBL24236924 | 0.81 | — | — | |
| Tromethamine SCHEMBL9718986 | 0.79 | MEN1 (0.42) | — | |
| SCHEMBL28486917 | 0.67 | — | — | |
| SCHEMBL10183871 | 0.65 | — | — | |
| SCHEMBL9862783 | 0.65 | — | — | |
| SCHEMBL16037462 | 0.64 | ALDH1A1 (1.00) | — | |
| SCHEMBL56391 | 0.64 | — | — | |
| SCHEMBL2683512 | 0.60 | — | — | |
| SCHEMBL30321467 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716856-B1 | Therapeutic uses of 2',5'-oligoadenylate derivatives | UNIV TEMPLE (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0420872-B1 | THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES | UNIV TEMPLE (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0716856-A2 | Therapeutic uses of 2',5'-oligoadenylate derivatives | Temple University of the Commonwealth System of Higher Education (US) | 1996-06-19 | — | — | EP | disclosed |