SCHEMBL7815949

SCHEMBL7815949

CCOc1cccc2c1C(=N)NC2=N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.46
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
APAF1 O14727 1/20 0.40
USP2 O75604 1/20 0.40
GAA P10253 1/20 0.40
THRB P10828 1/20 0.40
CASP1 P29466 1/20 0.40
BRCA1 P38398 1/20 0.40
CASP7 P55210 1/20 0.40
KMT2A Q03164 1/20 0.40
TTR P02766 2/20 0.39
GRK6 P43250 1/20 0.37
PPARG P37231 1/20 0.37
STAT3 P40763 1/20 0.37
NCOA2 Q15596 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7823833 0.85 CYP1A2 (0.44) PDE5A
SCHEMBL7816512 0.83 MCHR1 (0.42) MAPTMEN1KMT2APDE5A
SCHEMBL9325025 0.82 PDK2 (0.34) PDK2
SCHEMBL3215387 0.81 ALDH1A1 (0.39) PDK2ALDH1A1MAPTKDM4EMEN1
SCHEMBL7830178 0.80 CA1 (0.46) PDK2ALDH1A1MAPTKDM4EMEN1
SCHEMBL7827110 0.79
SCHEMBL9323965 0.79 PDK2 (0.37) PDK2ALDH1A1MAPTKDM4EMEN1
SCHEMBL8210462 0.77 PDK2 (0.36) PDK2
SCHEMBL7822785 0.77 PDE5A (0.32) PDE5A
SCHEMBL7827640 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed