Sugi Predict

Sugi Predict / Compounds / SCHEMBL3215387

SCHEMBL3215387

SCHEMBL3215387

CCOc1ccc(OCC)c2c1C(=N)NC2=N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.39
▸ MAPT P10636 5/20 0.39
▸ KDM4E B2RXH2 4/20 0.39
▸ GAA P10253 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ USP2 O75604 2/20 0.39
▸ APAF1 O14727 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ BRCA1 P38398 1/20 0.39
▸ CASP7 P55210 1/20 0.39
▸ NQO1 P15559 1/20 0.37
▸ HSD17B10 Q99714 4/20 0.35
▸ MAPK1 P28482 3/20 0.35
▸ HPGD P15428 3/20 0.35
▸ L3MBTL1 Q9Y468 3/20 0.35
▸ POLB P06746 1/20 0.35
▸ PDK2 Q15119 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7815949 0.81 PDK2 (0.46) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL3226085 0.75 CA2 (0.45) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL11866181 0.74 PDE4B (0.38) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL11866185 0.74 PDE4B (0.38) ALDH1A1MAPTGAAMEN1KMT2A
SCHEMBL11616558 0.73 ALDH1A1 (0.41) ALDH1A1MAPTKDM4EHSD17B10L3MBTL1
SCHEMBL11617826 0.73 HMGCR (0.33) —
SCHEMBL4956744 0.72 PTGER4 (0.40) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL7824104 0.70 PDK2 (0.43) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL7823732 0.69 PDK2 (0.42) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL24194104 0.67 PIM1 (0.43) ALDH1A1MAPTKDM4EGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554392-B1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME MITSUBISHI PAPER MILLS LTD (JP) 2016-05-11 — — EP disclosed
CN-102917883-B Method for manufacturing Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD 2015-01-14 — — CN disclosed
US-8623785-B2 Thermal recording material and method for producing the same MITSUBISHI PAPER MILLS LIMITED (JP) 2014-01-07 — — US disclosed
US-20130053240-A1 THERMAL RECORDING MATERIAL AND METHOD FOR PRODUCING THE SAME MITSUBISHI PAPER MILLS LIMITED (JP) 2013-02-28 — — US disclosed
EP-2554392-A1 HEAT-SENSITIVE RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME Mitsubishi Paper Mills Limited (JP) 2013-02-06 — — EP disclosed
US-8183175-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2012-05-22 — — US disclosed
US-20100062195-A1 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2010-03-11 — — US disclosed
US-7322927-B2 Hybrid phthalocyanine derivatives and their uses BIOSITE, INC. (US) 2008-01-29 — — US disclosed
US-20070026259-A1 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2007-02-01 — — US disclosed
US-20060228748-A1 Hybrid phthalocyanine derivatives and their uses BIOSITE INCORPORATED 2006-10-12 — — US disclosed
US-5763189-A Fluorescence energy transfer and intramolecular energy transfer in particles using novel compounds BIOSITE DIAGNOSTICS INCORPORATED (US) 1998-06-09 — — US disclosed
EP-0820489-A1 HYBRID PHTHALOCYANINE DERIVATIVES AND THEIR USES BIOSITE DIAGNOSTICS INC. (US) 1998-01-28 — — EP disclosed
EP-0670041-A4 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS. BIOSITE DIAGNOSTICS INC (US) 1997-11-05 — — EP disclosed
WO-1996029367-A1 HYBRID PHTHALOCYANINE DERIVATIVES AND THEIR USES BIOSITE DIAGNOSTICS INCORPORATED (US) 1996-09-26 — — WO disclosed
EP-0670041-A1 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS BIOSITE DIAGNOSTICS INC. (US) 1995-09-06 — — EP disclosed
WO-1995008772-A1 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS BIOSITE DIAGNOSTICS INCORPORATED (US) 1995-03-30 — — WO disclosed
US-4122261-A Polycyclic iminoisoindoline chelates STERLING DRUG INC. (US) 1978-10-24 — — US disclosed
US-4066653-A 1-IMINO-3-(4-IMINO-5-THIAZOLIDINYLIDENE)ISOINDOLINES STERLING DRUG INC. (US) 1978-01-03 — — US disclosed
US-3993658-A Thiazolidinylidene-isoindolines STERLING DRUG INC. (US) 1976-11-23 — — US disclosed
US-3966753-A Thiazolidinylidene isoindoline pigments STERLING DRUG INC. (US) 1976-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060228748-A1 Hybrid phthalocyanine derivatives and their uses UACA, PHAX, PTBP1 ALDH1A1 1368/4885MAPT 1005/4885KDM4E 4610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.