Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 7/20 | 0.56 |
| ▸ | PNP | P00491 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812589 | 0.88 | PNP (0.53) | TYMSPNPMEN1KMT2ATLR7 | |
| SCHEMBL7806221 | 0.86 | TYMS (0.59) | TYMSPNPMEN1KMT2ATLR7 | |
| SCHEMBL7813638 | 0.85 | TYMS (0.60) | TYMSPNPMEN1KMT2ABRAF | |
| SCHEMBL8165318 | 0.81 | PNP (0.70) | TYMSPNPMEN1KMT2ATLR7 | |
| SCHEMBL2127107 | 0.80 | PNP (0.57) | TYMSPNPTLR7ADORA3 | |
| SCHEMBL3672658 | 0.73 | PNP (0.61) | TYMSPNPMEN1KMT2ATLR7 | |
| SCHEMBL8177048 | 0.72 | MAPT (0.40) | PNPMEN1KMT2A | |
| SCHEMBL2435848 | 0.72 | PNP (0.43) | PNPMEN1KMT2A | |
| SCHEMBL1713573 | 0.71 | PNP (0.64) | TYMSPNPKMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL7773119 | 0.70 | PNP (0.63) | TYMSPNPKMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728757-B1 | Process for producing purine derivatives | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6245910-B1 | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| WO-2000006573-A1 | ANTIVIRAL ALKYL SUBSTITUTED PURINE DERIVATIVES AND THEIR PREPARATION | Kemijski inštitut (SI) | 2000-02-10 | — | — | WO | disclosed |
| EP-0827960-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1998-03-11 | — | — | EP | disclosed |
| EP-0728757-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1996-08-28 | — | — | EP | disclosed |