Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 10/20 | 0.60 |
| ▸ | DHFR | P00374 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816005 | 0.85 | TYMS (0.56) | TYMSBRAFMEN1KMT2APNP | |
| SCHEMBL7806221 | 0.83 | TYMS (0.59) | TYMSDHFRMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7813292 | 0.74 | DHFR (0.56) | TYMSDHFRL3MBTL1POLBMEN1 | |
| SCHEMBL7812589 | 0.73 | PNP (0.53) | TYMSBRAFMEN1KMT2APNP | |
| Bromide SCHEMBL7940873 | 0.73 | TYMS (0.52) | TYMSDHFRL3MBTL1POLBBRAF | |
| SCHEMBL2435848 | 0.68 | PNP (0.43) | MEN1KMT2AMAPTPNP | |
| SCHEMBL8177048 | 0.68 | MAPT (0.40) | MEN1KMT2AKDM4EMAPTHTT | |
| SCHEMBL8165318 | 0.67 | PNP (0.70) | TYMSDHFRL3MBTL1MEN1KMT2A | |
| SCHEMBL28021120 | 0.66 | PNP (0.70) | TYMSDHFRMEN1KMT2APNP | |
| SCHEMBL2127107 | 0.66 | PNP (0.57) | TYMSPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728757-B1 | Process for producing purine derivatives | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6245910-B1 | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0728757-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1996-08-28 | — | — | EP | disclosed |