Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 10/20 | 0.39 |
| ▸ | NPC1 | O15118 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP10 | Q14694 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824084 | 0.92 | MAPT (0.42) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL7823532 | 0.83 | MAPT (0.42) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL8068471 | 0.83 | ALDH1A1 (0.36) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL7868341 | 0.81 | MAPT (0.40) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL7830193 | 0.81 | ALDH1A1 (0.35) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL7815755 | 0.79 | RECQL (0.40) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL7827925 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL5515200 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL8057711 | 0.78 | HTT (0.49) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL7822888 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |