SCHEMBL7817232

SCHEMBL7817232

CCCCCCCCOC(=O)CCC(=O)O.N=C1NC(=N)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HTR2C P28335 1/20 0.45
CYP2C19 P33261 1/20 0.44
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
PTPN11 Q06124 1/20 0.43
PLA2G4B P0C869 2/20 0.42
NAAA Q02083 1/20 0.42
DGKA P23743 1/20 0.42
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PPARG P37231 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9234035 0.95 CYP2C19 (0.46) LMNATSHRALDH1A1CYP2C19TP53
SCHEMBL7816656 0.84 SMN1; SMN2 (0.48) ALDH1A1CYP2C19POLB
Dodecanoate SCHEMBL7824704 0.84 GPR84 (0.53) TSHRALDH1A1HSD17B10PPARG
Biphenyl SCHEMBL15791667 0.83 TSHR (0.54) LMNATSHRALDH1A1HTR2CCYP2C19
SCHEMBL11054198 0.81 TSHR (0.53) LMNATSHRALDH1A1HTR2CCYP2C19
SCHEMBL3031778 0.79 HTR2C (0.66) TSHRALDH1A1HTR2CNAAADGKA
SCHEMBL9257236 0.79 HTR2C (0.66) TSHRALDH1A1HTR2CNAAADGKA
SCHEMBL187665 0.79 HTR2C (0.66) TSHRALDH1A1HTR2CNAAADGKA
SCHEMBL10868296 0.79 HTR2C (0.66) TSHRALDH1A1HTR2CNAAADGKA
SCHEMBL7954252 0.79 HTR2C (0.66) TSHRALDH1A1HTR2CNAAADGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed