SCHEMBL7816656

SCHEMBL7816656

CCOC(=O)CCC(=O)O.N=C1NC(=N)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
PTPN1 P18031 1/20 0.44
CYP4F2 P78329 2/20 0.43
CYP4A11 Q02928 2/20 0.43
ALOX5 P09917 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
PPID Q08752 1/20 0.40
ALDH1A1 P00352 2/20 0.40
TOP2A P11388 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NOTUM Q6P988 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid Diethyl Ester SCHEMBL27427009 0.94 SMN1; SMN2 (0.49) SMN1; SMN2PTPN1CYP4F2CYP4A11ALOX5
SCHEMBL9234035 0.86 CYP2C19 (0.46) SMN1; SMN2CYP2C19ALDH1A1L3MBTL1MEN1
Succinic Acid Monobenzyl Ester SCHEMBL9236945 0.84 ALDH1A1 (0.49) ALDH1A1POLBMAPTL3MBTL1MEN1
SCHEMBL7817232 0.84 LMNA (0.46) CYP2C19ALDH1A1POLB
Succinic Acid SCHEMBL7829045 0.84 APEX1 (0.48) SMN1; SMN2CYP1A2CYP2C19ALDH1A1POLB
Butyric Acid SCHEMBL7824759 0.81 HDAC3 (0.46) SMN1; SMN2ALOX5CYP2C19ALDH1A1MAPT
Toluene SCHEMBL242077 0.79 SMN1; SMN2 (0.57) SMN1; SMN2CYP4F2CYP4A11ALOX5ALDH1A1
Biphenyl SCHEMBL27737000 0.79 SMN1; SMN2 (0.57) SMN1; SMN2PTPN1CYP4F2CYP4A11CYP1A2
Benzene SCHEMBL2248161 0.79 SMN1; SMN2 (0.53) SMN1; SMN2CYP4F2CYP4A11CYP1A2ALDH1A1
Dodecanoate SCHEMBL7824704 0.76 GPR84 (0.53) PTPN1ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed