Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810089 | 0.91 | MAPT (0.53) | MAPTLMNAMAPK1TSHRUSP2 | |
| SCHEMBL7814051 | 0.90 | TSHR (0.68) | MAPTLMNAMAPK1TSHRUSP2 | |
| SCHEMBL7804413 | 0.88 | MAPT (0.60) | MAPTLMNAMAPK1TSHRUSP2 | |
| SCHEMBL7804363 | 0.84 | ALDH1A1 (0.54) | MAPTLMNATSHRUSP2NPC1 | |
| SCHEMBL7810104 | 0.84 | LMNA (0.67) | MAPTLMNAMAPK1TSHRUSP2 | |
| SCHEMBL19561830 | 0.81 | ALDH1A1 (0.73) | MAPTLMNAMAPK1TSHRUSP2 | |
| SCHEMBL7811526 | 0.80 | PARP10 (0.53) | MAPTLMNATSHRKCNA5NPC1 | |
| SCHEMBL7813512 | 0.80 | MAPT (0.55) | MAPTLMNATSHRUSP2NPC1 | |
| SCHEMBL7813535 | 0.79 | LMNA (0.70) | MAPTLMNAMAPK1TSHRUSP2 | |
| SCHEMBL7810124 | 0.79 | PARP10 (0.54) | LMNAKCNA5NPC1ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |