Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816227 | 0.88 | UCHL1 (0.42) | DCTPP1UCHL1SLC5A1SLC5A2PTGER4 | |
| SCHEMBL7815550 | 0.86 | SLC5A1 (0.47) | DCTPP1UCHL1SLC5A1SLC5A2MAPT | |
| SCHEMBL7825482 | 0.86 | HPGD (0.44) | DCTPP1UCHL1PTGER4MAPTHPGD | |
| SCHEMBL7827030 | 0.85 | UCHL1 (0.42) | DCTPP1UCHL1SLC5A1SLC5A2PTGER4 | |
| SCHEMBL7827679 | 0.83 | UCHL1 (0.40) | DCTPP1UCHL1SLC5A1SLC5A2PTGER4 | |
| SCHEMBL5515660 | 0.83 | UCHL1 (0.41) | UCHL1SLC5A1SLC5A2PTGER4MAPT | |
| SCHEMBL7827515 | 0.83 | KMT2A (0.42) | DCTPP1UCHL1PTGER4MAPTHPGD | |
| SCHEMBL7823440 | 0.83 | UCHL1 (0.41) | DCTPP1UCHL1PTGER4MAPTHPGD | |
| SCHEMBL7828209 | 0.81 | DCTPP1 (0.43) | DCTPP1UCHL1SLC5A1SLC5A2MAPT | |
| SCHEMBL7826821 | 0.81 | UCHL1 (0.40) | DCTPP1UCHL1SLC5A1SLC5A2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |