Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 10/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820796 | 0.86 | HPGD (0.44) | HPGDF2HRH3DRD2DRD4 | |
| Oxalic Acid SCHEMBL6173205 | 0.76 | F2 (0.76) | F2 | |
| SCHEMBL7818684 | 0.76 | DRD2 (0.41) | HPGDF2HRH3DRD2DRD4 | |
| SCHEMBL7820895 | 0.75 | S1PR1 (0.47) | F2HRH3 | |
| SCHEMBL3378826 | 0.72 | MAPK1 (0.53) | F2ACHE | |
| SCHEMBL7451351 | 0.71 | F2 (0.58) | F2HRH3DRD2 | |
| SCHEMBL7452879 | 0.69 | F2 (0.52) | F2HRH3ACHE | |
| SCHEMBL7830026 | 0.68 | F2 (0.51) | F2 | |
| SCHEMBL7452312 | 0.67 | F2 (0.62) | F2HRH3DRD2 | |
| SCHEMBL7352515 | 0.67 | S1PR1 (0.53) | F2HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |