Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352515 | 0.86 | S1PR1 (0.53) | S1PR1S1PR5F2HRH3CD274 | |
| SCHEMBL6172105 | 0.84 | F2 (0.65) | S1PR1S1PR5F2HRH3 | |
| SCHEMBL7825481 | 0.82 | F2 (0.45) | S1PR1S1PR5F2HRH3LTA4H | |
| SCHEMBL7818684 | 0.79 | DRD2 (0.41) | S1PR1S1PR5F2HRH3LTA4H | |
| SCHEMBL7818365 | 0.79 | S1PR1 (0.45) | S1PR1S1PR5F2HRH3CD274 | |
| SCHEMBL26009644 | 0.76 | S1PR1 (0.67) | S1PR1S1PR5HRH3LTA4HCD274 | |
| SCHEMBL7820186 | 0.76 | S1PR1 (0.46) | S1PR1S1PR5F2HRH3MCHR1 | |
| SCHEMBL7447052 | 0.76 | CD274 (0.55) | F2HRH3CD274 | |
| SCHEMBL7451351 | 0.75 | F2 (0.58) | F2HRH3 | |
| SCHEMBL7817465 | 0.75 | HPGD (0.47) | F2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |