Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813905 | 0.93 | ALDH1A1 (0.46) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7804444 | 0.92 | NAMPT (0.44) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7810075 | 0.91 | NAMPT (0.47) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7813624 | 0.90 | POLB (0.40) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7814015 | 0.90 | NAMPT (0.44) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7811486 | 0.90 | PPARG (0.49) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7809885 | 0.90 | POLB (0.41) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7817528 | 0.90 | NAMPT (0.49) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7804398 | 0.88 | PPARG (0.49) | NAMPTALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL7804294 | 0.88 | HPGD (0.39) | NAMPTALDH1A1HPGDSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |