Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19401259 | 0.90 | MEN1 (0.73) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL177039 | 0.90 | MEN1 (0.73) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6897315 | 0.88 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Bromide SCHEMBL11864024 | 0.88 | MEN1 (0.70) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| Alcohol SCHEMBL11200660 | 0.86 | SMN1; SMN2 (0.66) | MAPTKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL6265883 | 0.86 | SMN1; SMN2 (0.76) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| N-Benzylmethylamine SCHEMBL9792032 | 0.83 | MAPT (0.81) | MAPTKDM4ECYP3A4MEN1KMT2A | |
| N-Benzylmethylamine SCHEMBL8944589 | 0.81 | MAPT (0.77) | MAPTKDM4ECYP3A4MEN1KMT2A | |
| N-Benzylmethylamine SCHEMBL9871758 | 0.81 | MAPT (0.85) | MAPTKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL24334039 | 0.81 | CYP3A4 (0.94) | MAPTKDM4ECYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716473-B2 | Substituted benzotriazines and quinoxalines as inhibitors of P7OS6 kinase | SENTINEL ONCOLOGY LIMITED (GB) | 2014-05-06 | — | — | US | disclosed |
| US-20120071478-A1 | SUBSTITUTED BENZOTRIAZINES AND QUINOXALINES AS INHIBITORS OF P7OS6 KINASE | SENTINEL ONCOLOGY LIMITED (GB) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071478-A1 | SUBSTITUTED BENZOTRIAZINES AND QUINOXALINES AS INHIBITORS OF P7OS6 KINASE | CDK1, CDK2, CDK6 | MAPT 2114/4885KDM4E 1274/4885CYP3A4 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.