Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811390 | 0.83 | GAA (0.73) | SMN1; SMN2GAARAB9AALDH1A1MAPK1 | |
| SCHEMBL7804335 | 0.82 | TSHR (0.67) | SMN1; SMN2GAARAB9AALDH1A1MAPK1 | |
| SCHEMBL7813944 | 0.81 | MEN1 (0.61) | SMN1; SMN2ALDH1A1TSHRDRD2KMT2A | |
| SCHEMBL766164 | 0.80 | GAA (0.70) | SMN1; SMN2GAARAB9AALDH1A1MAPK1 | |
| SCHEMBL7811604 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2GAAALDH1A1TSHRDRD2 | |
| SCHEMBL7817548 | 0.79 | USP2 (0.60) | GAAALDH1A1TSHRDRD3KMT2A | |
| SCHEMBL27297524 | 0.77 | GAA (1.00) | SMN1; SMN2GAARAB9AALDH1A1MAPK1 | |
| SCHEMBL7810154 | 0.77 | MEN1 (0.60) | SMN1; SMN2ALDH1A1TSHRDRD2KMT2A | |
| SCHEMBL7810142 | 0.77 | POLB (0.60) | SMN1; SMN2ALDH1A1TSHRDRD2KMT2A | |
| SCHEMBL7814258 | 0.76 | TSHR (0.61) | SMN1; SMN2GAARAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |