Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 8/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811390 | 0.90 | GAA (0.73) | TSHRGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL7811644 | 0.83 | BCL9 (0.52) | TSHRGAA | |
| SCHEMBL7813655 | 0.82 | MAPT (0.59) | TSHRALDH1A1MAPK1MAPTHTR2A | |
| SCHEMBL7817547 | 0.82 | SMN1; SMN2 (0.62) | TSHRGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL7810139 | 0.81 | ALDH1A1 (0.54) | TSHRALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL27324525 | 0.80 | TSHR (0.77) | TSHRGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL7814229 | 0.79 | ALDH1A1 (0.46) | TSHRGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL9011011 | 0.79 | TSHR (0.62) | TSHRGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL7811529 | 0.79 | ALDH1A1 (0.56) | TSHRGAAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7810133 | 0.78 | GAA (0.51) | TSHRGAAALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |