Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817551 | 0.89 | KCNA5 (0.58) | LMNANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7811430 | 0.88 | TSHR (0.54) | TSHRLMNANPC1HPGDAKR1C1 | |
| SCHEMBL7804419 | 0.86 | NPC1 (0.51) | NPC1HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL7810095 | 0.85 | TSHR (0.53) | TSHRLMNANPC1HPGDAKR1C1 | |
| SCHEMBL9011146 | 0.83 | NPC1 (0.65) | TSHRLMNANPC1HPGDAKR1C1 | |
| SCHEMBL7813987 | 0.81 | ALDH1A1 (0.55) | LMNAMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL9010991 | 0.81 | NPC1 (0.62) | TSHRLMNANPC1HPGDAKR1C1 | |
| SCHEMBL7814140 | 0.81 | NPC1 (0.50) | TSHRLMNANPC1HPGDAKR1C1 | |
| SCHEMBL7804403 | 0.81 | DRD4 (0.56) | TSHRLMNANPC1HPGDAKR1C1 | |
| SCHEMBL4310722 | 0.79 | TSHR (0.84) | TSHRLMNANPC1HPGDAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |