Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804419 | 0.91 | NPC1 (0.51) | KCNA5MAOBNPC1DRD3MEN1 | |
| SCHEMBL7817569 | 0.89 | TSHR (0.56) | KCNA5NPC1DRD3MEN1KMT2A | |
| SCHEMBL7813987 | 0.82 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1USP2LMNA | |
| SCHEMBL7811430 | 0.77 | TSHR (0.54) | KCNA5NPC1DRD3MEN1KMT2A | |
| SCHEMBL7804532 | 0.76 | KCNA5 (0.52) | KCNA5NPC1DRD3MEN1KMT2A | |
| SCHEMBL7804380 | 0.76 | KCNA5 (0.52) | KCNA5NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9557309 | 0.76 | PKM (0.53) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL7129676 | 0.73 | HPGD (0.79) | MAOBMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL252026 | 0.73 | HPGD (0.79) | MAOBMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL7810095 | 0.73 | TSHR (0.53) | KCNA5NPC1DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |