Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 5/20 | 0.63 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.63 |
| ▸ | RORC | P51449 | 15/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7956334 | 0.99 | BDKRB2 (0.62) | BDKRB2BDKRB1RORC | |
| SCHEMBL7811200 | 0.94 | RORC (0.61) | BDKRB2BDKRB1RORC | |
| Hydrochloric Acid SCHEMBL7954327 | 0.93 | RORC (0.60) | BDKRB2BDKRB1RORC | |
| SCHEMBL7814484 | 0.92 | RORC (0.63) | BDKRB2BDKRB1RORC | |
| Hydrochloric Acid SCHEMBL7954315 | 0.91 | RORC (0.62) | BDKRB2BDKRB1RORC | |
| SCHEMBL7810522 | 0.91 | RORC (0.69) | BDKRB2RORC | |
| SCHEMBL7814891 | 0.90 | BDKRB2 (0.77) | BDKRB2BDKRB1RORC | |
| Hydrochloric Acid SCHEMBL7952866 | 0.90 | RORC (0.68) | BDKRB2RORC | |
| Hydrochloric Acid SCHEMBL8174819 | 0.89 | BDKRB2 (0.76) | BDKRB2BDKRB1RORC | |
| Hydrochloric Acid SCHEMBL7954912 | 0.89 | BDKRB2 (0.76) | BDKRB2BDKRB1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874841-B1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |