Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | FABP3 | P05413 | 3/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818507 | 0.88 | ELANE (0.46) | MEN1KMT2AC1RS100A4TUBB4A | |
| SCHEMBL6516391 | 0.85 | PDE4B (0.43) | MEN1KMT2AHTTSMN1; SMN2TUBB4A | |
| SCHEMBL12781496 | 0.84 | PABPC1 (0.47) | MEN1KMT2AC1RLMNAHTT | |
| SCHEMBL7820175 | 0.82 | TP53 (0.51) | KDM4EMEN1KMT2AC1RLMNA | |
| SCHEMBL24122668 | 0.81 | ADORA2A (0.50) | KDM4EMEN1KMT2AFABP4FABP3 | |
| SCHEMBL7821797 | 0.81 | KMT2A (0.51) | MEN1KMT2AS100A4IDO1TDO2 | |
| SCHEMBL7820606 | 0.78 | MEN1 (0.49) | KDM4EMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16895274 | 0.78 | APAF1 (0.48) | KDM4EMEN1KMT2AC1RS100A4 | |
| SCHEMBL3732268 | 0.78 | PABPC1 (0.47) | MEN1KMT2AC1RLMNAHTT | |
| SCHEMBL7818757 | 0.77 | TOP1 (0.56) | KDM4EMEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713870-B1 | NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-6028079-A | FOR TREATING TUMOR OF MAMMAL | TAIHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5733918-A | ANTITUMOR AGENT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| US-5710162-A | ANTITUMOR AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0713870-A1 | NOVEL FUSED INDAN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-29 | — | — | EP | disclosed |