Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 8/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743897 | 0.80 | CA12 (0.39) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL11650931 | 0.80 | CA12 (0.39) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL3602153 | 0.77 | CA12 (0.36) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL4696736 | 0.75 | — | — | |
| SCHEMBL3283747 | 0.75 | CA12 (0.35) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL3283303 | 0.75 | ZDHHC20 (0.42) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL6196640 | 0.74 | KDM5A (0.36) | KDM5AKDM4CPHF8AKR1B1ALOX15 | |
| Hydrochloric Acid SCHEMBL21597897 | 0.73 | — | — | |
| SCHEMBL23685726 | 0.72 | CA12 (0.39) | CA12CA1CA9MMP1MMP2 | |
| SCHEMBL22750272 | 0.72 | KDM5A (0.38) | KDM5AKDM4CPHF8AKR1B1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124827-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024739-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |