Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 8/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648404 | 0.92 | GPR84 (0.40) | KDM5AKDM4CALDH1A1PHF8ALOX15 | |
| SCHEMBL11650931 | 0.87 | CA12 (0.39) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL3602153 | 0.83 | CA12 (0.36) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL7818338 | 0.80 | CA12 (0.40) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL27376019 | 0.79 | CA12 (0.48) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL22750272 | 0.79 | KDM5A (0.38) | KDM5AKDM4CALDH1A1PHF8AKR1B1 | |
| SCHEMBL30771785 | 0.78 | DNM1 (0.40) | KDM5AKDM4CALDH1A1PHF8ALOX15 | |
| SCHEMBL28383235 | 0.77 | CA12 (0.46) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL28420750 | 0.77 | CA12 (0.46) | CA12CA1CA9KDM5AKDM4C | |
| SCHEMBL28569938 | 0.77 | ALDH1A1 (0.33) | ALDH1A1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3114109-A1 | INHIBITORS OF HISTONE LYSINE SPECIFIC DEMETHYLASE (LSD1) AND HISTONE DEACETYLASES (HDACS) | The Johns Hopkins University (US) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015134973-A1 | INHIBITORS OF HISTONE LYSINE SPECIFIC DEMETHYLASE (LSD1) AND HISTONE DEACETYLASES (HDACS) | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-11 | — | — | WO | disclosed |
| EP-1095001-A4 | METHOD OF VITAMIN PRODUCTION | DCV INC (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1095002-A1 | METHOD OF VITAMIN PRODUCTION | DCV Inc. doing business as Bio-Technical Resourses (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-1095001-A1 | METHOD OF VITAMIN PRODUCTION | DCV Inc. doing business as Bio-Technical Resourses (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001649-A1 | METHOD OF VITAMIN PRODUCTION | DCV, INC. DOING BUSINESS AS BIO-TECHNICAL RESOURCES (US) | 2000-01-13 | — | — | WO | disclosed |
| WO-2000001650-A1 | METHOD OF VITAMIN PRODUCTION | DCV, INC. DOING BUSINESS AS BIO-TECHNICAL RESOURCES (US) | 2000-01-13 | — | — | WO | disclosed |