Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811966 | 0.93 | PPARG (0.57) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL7811918 | 0.91 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL7822293 | 0.90 | PPARG (0.59) | PPARGKCNH2 | |
| SCHEMBL7811590 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL7818527 | 0.89 | PPARG (0.55) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL7820066 | 0.89 | PPARG (0.55) | AGTR1AGTR2PPARGKCNH2 | |
| SCHEMBL7818935 | 0.87 | PPARG (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL7819420 | 0.87 | PPARG (0.59) | PPARGKCNH2 | |
| SCHEMBL7819781 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL7818874 | 0.85 | PPARG (0.53) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781276-A1 | PYRIMIDINONE DERIVATIVES | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 1997-07-02 | — | — | EP | claimed |
| WO-1996008476-A1 | PYRIMIDINONE DERIVATIVES | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 1996-03-21 | — | — | WO | claimed |
| EP-0781276-B1 | PYRIMIDINONE DERIVATIVES | BORYUNG PHARM (KR) | 2001-12-12 | — | — | EP | disclosed |