SCHEMBL7822293

SCHEMBL7822293

CCCCc1nc(C)c(CCC(=O)OCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.59
KCNH2 Q12809 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7819420 0.97 PPARG (0.59) PPARGKCNH2
SCHEMBL7818874 0.95 PPARG (0.53) PPARG
SCHEMBL7810831 0.93 PPARG (0.68) PPARGKCNH2
SCHEMBL7820768 0.93 PPARG (0.50) PPARG
SCHEMBL7818527 0.92 PPARG (0.55) PPARGKCNH2
SCHEMBL7820066 0.92 PPARG (0.55) PPARGKCNH2
SCHEMBL7818608 0.91 PPARG (0.57) PPARG
SCHEMBL9843837 0.91 AGTR1 (0.59) PPARG
SCHEMBL7818688 0.90 AGTR1 (0.58) PPARG
SCHEMBL7818403 0.90 AGTR1 (0.51) PPARGKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0781276-A1 PYRIMIDINONE DERIVATIVES BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1997-07-02 EP claimed
WO-1996008476-A1 PYRIMIDINONE DERIVATIVES BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1996-03-21 WO claimed
EP-0781276-B1 PYRIMIDINONE DERIVATIVES BORYUNG PHARM (KR) 2001-12-12 EP disclosed
EP-0781276-A1 PYRIMIDINONE DERIVATIVES BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1997-07-02 EP disclosed
WO-1996008476-A1 PYRIMIDINONE DERIVATIVES BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1996-03-21 WO disclosed