Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | GSK3A | P49840 | 3/20 | 0.67 |
| ▸ | GSK3B | P49841 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479141 | 0.81 | GSK3B (1.00) | ALDH1A1KDM4EGSK3AGSK3BMAPT | |
| SCHEMBL16479138 | 0.81 | GSK3B (1.00) | ALDH1A1KDM4EGSK3AGSK3BMAPT | |
| SCHEMBL16479137 | 0.81 | GSK3B (1.00) | ALDH1A1KDM4EGSK3AGSK3BMAPT | |
| SCHEMBL16460212 | 0.81 | GSK3B (0.71) | ALDH1A1KDM4EGSK3AGSK3BRECQL | |
| SCHEMBL20539127 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EGSK3AGSK3BRECQL | |
| SCHEMBL8185796 | 0.78 | MAPT (0.51) | ALDH1A1KDM4EGSK3AGSK3BGAA | |
| SCHEMBL8192885 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4EGSK3AGSK3BGAA | |
| SCHEMBL7817207 | 0.77 | HSD17B10 (0.65) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL7814667 | 0.76 | MAPT (0.73) | ALDH1A1KDM4EGSK3AGSK3BGAA | |
| SCHEMBL6029604 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EGSK3AGSK3BRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |