Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010448 | 0.85 | KDM4E (0.56) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL15435872 | 0.85 | GPR174 (0.62) | HSD17B10KDM4ETSHRGAAMAPT | |
| SCHEMBL2998592 | 0.78 | KDM4E (1.00) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL7818487 | 0.77 | ALDH1A1 (0.67) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL3324020 | 0.76 | KDM4E (0.78) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL7817258 | 0.74 | GPR174 (0.72) | ALDH1A1GAAFFAR3MAPTABCC9 | |
| SCHEMBL3326098 | 0.74 | KDM4E (0.80) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL3242208 | 0.74 | FFAR3 (0.70) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL7678904 | 0.73 | HSD17B10 (0.42) | HSD17B10KDM4EALDH1A1TSHRHPGD | |
| SCHEMBL8741578 | 0.71 | ABCC9 (0.65) | HSD17B10KDM4EMAPTABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | claimed |
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |