Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7810172 | 0.99 | EHMT2 (0.39) | EHMT2EHMT1ADORA2ANPC1TP53 | |
| SCHEMBL7820042 | 0.94 | ADORA2A (0.38) | EHMT2EHMT1ADORA2AKDM4EGLA | |
| Hydrochloric Acid SCHEMBL7819843 | 0.93 | ADORA2A (0.37) | EHMT2EHMT1ADORA2AKDM4EGLA | |
| SCHEMBL7810189 | 0.84 | EHMT2 (0.38) | EHMT2EHMT1NPC1TP53HPGD | |
| SCHEMBL7811938 | 0.83 | ADORA2A (0.42) | ADORA2ANPC1HPGDKDM4EGLA | |
| SCHEMBL7811946 | 0.83 | ADORA2A (0.42) | ADORA2ANPC1HPGDKDM4EGLA | |
| SCHEMBL7821140 | 0.83 | ADORA2A (0.42) | ADORA2ANPC1HPGDKDM4EGLA | |
| Hydrochloric Acid SCHEMBL7819979 | 0.83 | EHMT2 (0.38) | EHMT2EHMT1NPC1TP53HPGD | |
| SCHEMBL7820492 | 0.81 | MAPT (0.49) | EHMT2EHMT1NPC1TP53HPGD | |
| Hydrochloric Acid SCHEMBL7820964 | 0.80 | MAPT (0.48) | EHMT2EHMT1NPC1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | claimed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | claimed |
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |