Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7819979 | 0.99 | EHMT2 (0.38) | EHMT2EHMT1MERTKAURKASRC | |
| SCHEMBL6991158 | 0.84 | L3MBTL1 (0.36) | EHMT2EHMT1L3MBTL1NPC1RAB9A | |
| SCHEMBL7818490 | 0.84 | EHMT2 (0.40) | EHMT2EHMT1NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL6999560 | 0.83 | L3MBTL1 (0.36) | EHMT2EHMT1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6990607 | 0.83 | L3MBTL1 (0.36) | EHMT2EHMT1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6990610 | 0.83 | L3MBTL1 (0.36) | EHMT2EHMT1L3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7810172 | 0.83 | EHMT2 (0.39) | EHMT2EHMT1NPC1RAB9AMAPT | |
| SCHEMBL7824698 | 0.81 | EGFR (0.43) | MAPTALDH1A1CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL6997882 | 0.81 | NPC1 (0.36) | L3MBTL1NPC1RAB9AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6994238 | 0.80 | L3MBTL1 (0.36) | EHMT2EHMT1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | claimed |
| EP-0677049-B1 | QUINAZOLINE DERIVATIVES | YUHAN CORP LTD (KR) | 2001-07-25 | — | — | EP | disclosed |
| US-5686458-A | Quinazoline deriviates for treating peptic ulcer | YUHAN CORPORATION (KR) | 1997-11-11 | — | — | US | disclosed |
| EP-0677049-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014795-A1 | QUINAZOLINE DERIVATIVES | YUHAN CORPORATION (KR) | 1994-07-07 | — | — | WO | disclosed |