Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8173505 | 0.98 | MAOB (0.45) | MAOBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7815094 | 0.88 | MAOB (0.50) | MAOBCA1CA2CA9CA7 | |
| Hydrochloric Acid SCHEMBL8173515 | 0.86 | MAOB (0.48) | MAOBCA1CA2CA9CA7 | |
| SCHEMBL11508814 | 0.82 | GRIN2D (0.61) | MAOBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11508214 | 0.79 | HTR2A (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6948271 | 0.79 | MAOB (0.54) | MAOBCA1CA2CA9CA7 | |
| SCHEMBL19849879 | 0.78 | MAOB (0.48) | MAOBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3678682 | 0.78 | MAOA (0.62) | MAOAHTR2AAKT2HRH1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7719897 | 0.77 | MAOB (0.52) | MAOBCA1CA2CA9CA7 | |
| SCHEMBL7385516 | 0.75 | MAPT (0.54) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |