Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818681 | 1.00 | GRB2 (0.45) | GRB2PTPN1FFAR1KIF11USP2 | |
| SCHEMBL18035915 | 0.82 | GRB2 (0.46) | GRB2PTPN1KIF11MEN1KMT2A | |
| SCHEMBL2900362 | 0.80 | GRB2 (0.52) | GRB2PTPN1FFAR1KIF11USP2 | |
| SCHEMBL2900363 | 0.80 | GRB2 (0.52) | GRB2PTPN1FFAR1KIF11USP2 | |
| SCHEMBL5327704 | 0.80 | SLC7A5 (0.50) | USP2PKMMEN1KMT2AALOX15 | |
| SCHEMBL5327701 | 0.80 | SLC7A5 (0.50) | USP2PKMMEN1KMT2AALOX15 | |
| SCHEMBL2265488 | 0.80 | USP2 (0.44) | USP2PKMMEN1KMT2AALOX15 | |
| SCHEMBL10697710 | 0.79 | GRB2 (0.38) | GRB2PTPN1USP2PKMMEN1 | |
| SCHEMBL16163463 | 0.78 | GRB2 (0.50) | GRB2PTPN1KIF11USP2PKM | |
| SCHEMBL1311116 | 0.78 | GRB2 (0.57) | GRB2PTPN1KIF11USP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258973-B1 | OXIDATION | RHONE-POULENC AGRO (FR) | 2001-07-10 | — | — | US | claimed |