Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818683 | 0.79 | GRB2 (0.45) | GRB2MEN1KMT2AUSP2PKM | |
| SCHEMBL7818681 | 0.79 | GRB2 (0.45) | GRB2MEN1KMT2AUSP2PKM | |
| SCHEMBL5327701 | 0.75 | SLC7A5 (0.50) | MEN1KMT2AUSP2PKMALOX15 | |
| SCHEMBL5327704 | 0.75 | SLC7A5 (0.50) | MEN1KMT2AUSP2PKMALOX15 | |
| SCHEMBL2265488 | 0.75 | USP2 (0.44) | MEN1KMT2AUSP2PKMALOX15 | |
| SCHEMBL29398675 | 0.70 | SLC7A5 (0.55) | MEN1KMT2APKMALOX15HSD17B10 | |
| SCHEMBL29397997 | 0.70 | SLC7A5 (0.55) | MEN1KMT2APKMALOX15HSD17B10 | |
| SCHEMBL28839577 | 0.70 | SLC7A5 (0.55) | MEN1KMT2APKMALOX15HSD17B10 | |
| SCHEMBL11062896 | 0.69 | CA2 (0.57) | MEN1KMT2ATDP1CYP3A4CYP2C9 | |
| SCHEMBL10499080 | 0.69 | ALDH1A1 (0.44) | MEN1KMT2ACYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |